Upon its release, "Main Hoon Na" emerged as a significant commercial success, contributing to its position as one of the top-grossing films of 2004. The movie's dialogues, penned by Nirmal Soni and Nipun Dhingra, are remembered for their humor and emotional depth. The soundtrack, composed by Shankar-Ehsaan-Loy, features hit songs that remain popular even years after the film's release.