The series revolves around the story of a protagonist who finds himself transported into a labyrinthine world, a common trope in isekai stories. However, what sets "Isekai Meikyuu de Harem wo" apart is its focus on building a harem of companions within this labyrinthine world. The concept of a harem, where a single male protagonist is surrounded by multiple female characters who are romantically interested in him, is a popular theme in anime and manga.